Publication: Diagnostic Dilemma of Widespread Vesiculobullous Lesions: A Case Report Authors
Date
2022
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract:
Stevens-Johnson syndrome and toxic epidermal necrolysis represent a spectrum of severe mucocutaneous reactions, while Acute Cutaneous Lupus Erythematosus is a variant of Systemic Lupus Erythematosus. Both are rare conditions, with significant morbidity and mortality; often indistinguishable clinically and pose a diagnostic dilemma for the clinician. We hereby present a unique case of a 17 years old female who presented with widespread vesiculobullous lesions with peeling, desquamation, and crusting of the skin surface, non-scarring alopecia, oral and nasal ulcers, as well as two episodes of generalized tonic-clonic seizures. The patient had a history of intake of itraconazole tablets for a week, 25 days before the disease manifestation.
Description
Nisha Khadka
Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal
https://orcid.org/0000-0003-0580-377X
Subij Shakya
Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal
Dikshya Khatiwada
Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal
https://orcid.org/0000-0003-4843-1048
Pravash Budhathoki
Department of Internal Medicine, Bronx Lebanon Hospital, USA
Tulsi Ram Bhattarai
Department of Internal Medicine, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal
Keywords
case report, cutaneous lupus erythematosus, rheumatology, stevens-johnson syndrome.