Publication: Risk Factors and Outcome of Neonates Born through Meconium Stained Amniotic Fluid in a Tertiary Hospital of Nepal
Date
2015
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Paediatric Society (JNPS)
Abstract
Abstract:
Introduction: The incidence of meconium aspiration syndrome is still high in the developing world contributing significantly to the neonatal mortality. The study was aimed to know the risk factors contributing to meconium aspiration syndrome and neonatal outcome in a tertiary government hospital of the country.
Materials and Methods: It was a hospital based cross sectional study done over a period of three months. All live newborns born through meconium stained liquor were enrolled and all the details regarding mother, neonate were recorded. Odd’s ratio and bivariate analysis was done to assess the risk factors for meconium aspiration syndrome.
Result: Out of all the deliveries 14.6% were meconium stained amniotic fluid and meconium aspiration syndrome developed in 6.6% of the neonates. Low Apgar score and premature rupture of membranes was significantly associated with the risk of occurrence of meconium aspiration syndrome. Neonates who developed meconium aspiration syndrome had mortality of 11.3%.
Conclusion: Perinatal asphyxia and premature rupture of membranes were significantly associated with the development of meconium aspiration syndrome and neonates who developed meconium aspiration syndrome had high mortality.
Description
SM Gurubacharya
Chief Registrar, Associate Professor, Department of Neonatology, Paropakar Maternity and Women’s Hospital, Kathmandu
S Rajbhandari
Medical Officer, Department of Neonatology, Paropakar Maternity and Women’s Hospital, Kathmandu
R Gurung
Medical Officer, Department of Neonatology, Paropakar Maternity and Women’s Hospital, Kathmandu
A Rai
Medical Officer, Department of Neonatology, Paropakar Maternity and Women’s Hospital, Kathmandu
M Mishra
Medical Officer, Department of Neonatology, Paropakar Maternity and Women’s Hospital, Kathmandu
KR Sharma
Senior Consultant, Department of Neonatology, Paropakar Maternity and Women’s Hospital, Kathmandu
DR Aryal
Chief Consultant, Head of Department, Department of Neonatology, Paropakar Maternity and Women’s Hospital, Kathmandu
Keywords
Neonate, Meconium, Asphyxia