Publication: Wilson’s Disease with Lymphoproliferative Disorder: A Case Report
Date
2025
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract
Wilson's disease is characterized by copper accumulation in organs like liver, brain, and eyes, presenting with a varied clinical features, making it challenging to diagnose. This report describes a case of Wilson’s disease with unusual hematological features. A 12-year-old from Himalayan region presented with weakness, dysarthria, tremors. Initial investigations revealed pancytopenia, and bone marrow showed a lymphoproliferative disorder. He developed behavioral changes, a flat affect, and scanning speech. Wilson’s disease was confirmed through Kayser-Fleischer rings, reduced serum ceruloplasmin levels, and elevated urinary copper, supported by imaging.
Description
Ashish Jha
Madhesh Institute of Health Sciences, Janakpurdham, Dhanusha, Nepal
Saroj Kumar Sah
Kanti Childrens’ Hospital, Maharajgunj, Kathmandu, Nepal
Ravi Ranjan Pradhan
Beni Provincial Hospital, Beni, Myagdi, Nepal