Publication: Association of Birth Weight with Gestational Age and Maternal Measles Antibodies
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Date
2015
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Paediatric Society (JNPS)
Abstract
Abstract:
Introduction: Maternal measles antibody (MMA) offers protection against measles in early childhood, however, certain determinants of this antibody lives much to be desired. The aim of the study were to determine the association between birthweight (BW) and gestational age (GA), to assess the relationship between BW and MMA, to correlate GA with MMA and to examine the combined effects of BW and GA on MMA.
Material and Methods: The work was a hospital-based cross-sectional descriptive study. Babies were enrolled using systematic random sampling method. The babies BW was measured using the bassinet scale; enzyme linked immunosorbent assay was used to determine MMA. GA of babies was determined using the mothers' last menstrual period (LMP) or by Dubowitz score or by Obstetric ultrasound scan. Data were analysed using SPSS statistical software version 16, Illinois, Chicago USA and a computer program for epidemiologist PEPI version 3.01. Spearman’s correlation (rho), Kendall’s rank correlation (tau b) and Jonckheere-Terpstra test of association of ordinal variables were determined. Univariate analysis was used to investigate the combine effects of BW and GA on MMA. Likely-hood ratio Chisquare (?2) was used for categorical data. Goodman-Kruskal index rank order of predictive association (tau) of ordinal data was also calculated.
Results: 200 babies were enrolled, 101 (50.5%) were males and 99 (49.5%) females. 169 babies (84.5%) had normal BW, 117 (58.5%) were delivered at term. The mean BW was 3.04 (0.58) at 95% CI (2.96 – 3.12) kg. Association between BW and GA was significant (p=0.003), the predictive value for the association was also significant (p=0.039). Significant correlation was also observed between GA and MMA (p<0.001).
Conclusions: There was a significant association between BW and GA and MMA correlated well with GA.
Description
BU Ahmadu
Head of Department, Paediatrics, Federal Medical Centre Yola, P.M.B 2017, Yola, Adamawa State
Y Shemiya
Department of Paediatrics, Federal Medical Centre, Yola, Adamawa state
G Anita
Department of Paediatrics, Federal Medical Centre, Yola, Adamawa state
S Ubong
Department of Paediatrics, Federal Medical Centre, Yola, Adamawa state
B Abdulrahman
Department of Paediatrics, Federal Medical Centre, Yola, Adamawa state
B Amina
Department of Paediatrics, Federal Medical Centre, Yola, Adamawa state
Y Iranyang
Department of Paediatrics, Federal Medical Centre, Yola, Adamawa state
Z Rabi
Department of Paediatrics, Federal Medical Centre, Yola, Adamawa state
MA Chekwube
Department of Paediatrics, Federal Medical Centre, Yola, Adamawa state
MU Fatima
Department of Paediatrics, Federal Medical Centre, Yola, Adamawa state
A Gidado
Department of Paediatrics, Federal Medical Centre, Yola, Adamawa state
Keywords
Birthweight, Gestational age, Maternal measles antibody, Babies, Maiduguri, North-Eastern Nigeria