Publication: Sertoli Leydig Cell Tumour Initially Misdiagnosed as Polycystic Ovarian Syndrome and Congenital Adrenal Hyperplasia: A Case Report
| creativeworkseries.issn | JNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X | |
| dc.contributor.author | Paudyal, Pooja | |
| dc.contributor.author | Gurung, Geeta | |
| dc.contributor.author | Baral, Josie | |
| dc.contributor.author | Kharel, Nisha | |
| dc.date.accessioned | 2026-03-25T05:05:36Z | |
| dc.date.available | 2026-03-25T05:05:36Z | |
| dc.date.issued | 2020 | |
| dc.description | Pooja Paudyal Department of Obstetrics and Gynecology, Tribhuvan University Teaching Hospital (TUTH), Maharajgunj, Kathmandu, Nepal https://orcid.org/0000-0002-7522-0759 Geeta Gurung Department of Obstetrics and Gynecology, Tribhuvan University Teaching Hospital (TUTH), Maharajgunj, Kathmandu, Nepal Josie Baral Department of Obstetrics and Gynecology, Tribhuvan University Teaching Hospital (TUTH), Maharajgunj, Kathmandu, Nepal Nisha Kharel Department of Obstetrics and Gynecology, Tribhuvan University Teaching Hospital (TUTH), Maharajgunj, Kathmandu, Nepal | |
| dc.description.abstract | Abstract: Sertoli-Leydig cell tumor of the ovary is an unusual neoplasm that belongs to a group of sex cord-stromal tumors of the ovary and accounts for less than 0.5% of all primary ovarian neoplasms. They are often characterized by the presence of mass with androgen production and signs of virilization. Due to the substantially low incidence of Sertoli-Leydig cell tumors, information on clinical behavior, prognostic factors, and optimal management arelimited. Here in, we report a case of aprimary ovarian Sertoli-Leydig cell tumor in a 21-year-old student, previously diagnosed to have polycystic ovarian syndrome and subsequently congenital adrenal hyperplasia, who presented with a large abdominal mass and features of virilization along with elevated serum testosterone levels. Fertility sparing unilateral salpingo-oophorectomy was done and adjuvant chemotherapy was given after histopathology showed moderate to poorly differentiated Sertoli-Leydig cell tumor. Following surgery, her features of hyperandrogenism resolved and serum testosterone levels returned to normal. | |
| dc.identifier | https://doi.org/10.31729/jnma.5045 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/5399 | |
| dc.language.iso | en_US | |
| dc.publisher | Nepal Medical Association | |
| dc.subject | hyperandrogenism | |
| dc.subject | Sertoli-Leydig cell tumor | |
| dc.subject | tumor differentiation | |
| dc.title | Sertoli Leydig Cell Tumour Initially Misdiagnosed as Polycystic Ovarian Syndrome and Congenital Adrenal Hyperplasia: A Case Report | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Case Report | |
| oaire.citation.endPage | 926 | |
| oaire.citation.startPage | 923 | |
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