Publication: Portal Hypertension among Patients with Chronic Liver Disease Admitted to the Department of Internal Medicine of a Tertiary Care Centre
Date
2023
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract
Introduction: Portal hypertension is increased pressure within the portal vein. A portal pressure gradient of more than 10 mmHg is defined as "clinically significant portal hypertension" due to manifestations such as splenomegaly, gastroesophageal varices, ascites, hepatorenal syndrome, hepatopulmonary syndrome, hepatic encephalopathy, and spontaneous bacterial peritonitis. The aim of this study was to find out the prevalence of portal hypertension among patients with chronic liver disease admitted to the Department of Internal Medicine of a tertiary care centre.
Methods: A descriptive cross-sectional study was conducted among patients with chronic liver disease in the Department of Internal Medicine of a tertiary care centre from 1 January 2021 to 31 December 2022 after obtaining ethical approval from the Institutional Review Committee. Convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval.
Results: Among 247 patients with chronic liver disease, the prevalence of portal hypertension was 38 (15.38%) (10.88-19.88, 95% Confidence Interval). A total of 16 (42.11%) patients were in the age group of 51-60 years and males were 36 (94.74%). Ascites as a complication were found in 4 (10.53%).
Conclusions: The prevalence of portal hypertension among chronic liver disease inpatients in a tertiary care centre was found to be lower than other studies done in international settings.
Description
Sabina Khadka
Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal
Ananda Aryal
All Nepal Hospital, Samakhusi, Kathmandu, Nepal
Sagun Karki
Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal
Pratik Subedi
Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal
Kanchan Bogati
Oxford University Clinical Research Unit, Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal
Sunil Baniya
Oxford University Clinical Research Unit, Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal
Shrekshya Khadka
Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal
Kumar Roka
Department of Internal Medicine, Shree Birendra Hospital, Chhauni, Kathmandu, Nepal
Asha Shahi
Naubise Health Post, Dhunibesi, Dhading, Nepal