Publication: Risk Factors Associated with Childhood Asthma - A Case Control Study
Date
2018
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Background
Asthma is one of the most common chronic childhood illnesses with rapidly
increasing prevalence in low income countries. For planning effective intervention to
reverse this condition we need a better understanding of the risk factors for asthma
in early life.
Objective
To identify the risk factors associated with childhood asthma and its morbidity
patterns.
Method
The case control study was conducted in the pediatric department of Dhulikhel
hospital, Kathmandu University hospital, Dhulikhel from March 2016 to March
2017. The control group was composed of 175 age matched children attending the
outpatient clinic with non pulmonary health problem. Data was collected through
Performa and analyzed using SPSS version 23. The association of asthma with genetic
and environmental risk factors was evaluated by univariant (chi-square or Fisher’s
exact test) and binomial logistic regression.
Result
Childhood asthma was more common in male children between 1-5 years. Majority
of children 77(44%) were graded as mild persistent asthma. Risk factor associated
with asthma include family history of asthma (OR0.06; 95%CI .005-0.94, p=0.04),
nonexclusive breast feeding (OR18.42; 95% CI 2.56-132.3, p=0.004), allergic disorder
in children (OR0.003; 95%CI 0.000-0.037, p=0.0001).
Conclusion
Family history of asthma, allergic history in the patient and nonexclusive breast
feeding were significantly associated with asthma. There is no significant association
of asthma with exposure to allergic food, exposure to smoke and domestic animals.
KEY WORDS
Breastfeeding, Childhood asthma, Risk factor
Description
Dongol Singh S, Shrestha A
Department of Pediatrics
Kathmandu University School of Medical Sciences
Dhulikhel, Kavre, Nepal
Keywords
Breastfeeding, Childhood asthma, Risk factor