Publication: A study of sensitivity and resistance of pathogenic micro organisms causing UTI in Kathmandu valley
| creativeworkseries.issn | 1812-2027 | |
| dc.contributor.author | N, Jha | |
| dc.contributor.author | S K, Bapat | |
| dc.date.accessioned | 2025-07-17T05:40:57Z | |
| dc.date.available | 2025-07-17T05:40:57Z | |
| dc.date.issued | 2005 | |
| dc.description.abstract | A retrospective study was conducted in five hospitals to observe the prevalence of organisms causing UTI and their sensitivity to antibiotics. Methodology: Altogether, data from five hundred samples of urine from five hospitals in Kathmandu was collected for this study from January 2005 to April 2005. Result: A total of 244 samples were found to be positive. Altogether six types of organisms were isolated as the causative factors. E. coli (49%), S. aureus, (coagulase positive) (23%), Proteus species (3.6%), Klebsiella (9.71%), Pseudomonas (0.8%) and Citrobacter (2.8%). Analysis of the samples showed that UTI was more common in females of younger age group as comp ared to males. The common age group for females was 21-30 years, whereas that for males was 31-40 years in all the hospitals except in hospital A, where the maximum number of females was from 31-40 years and males were between 71-80 years. The most common organism to cause UTI was found to be E. coli (49%), followed by S. aureus (23%) and Klebsiella (9.71%). All the organisms causing UTI were sensitive to nitrofurantoin and amoxycillin and ciprofloxacin was found to be least effective. Similarly, in three hospitals, B (88.2%), D (64.7%) and E (65.3%), amoxycillin was found to be most effective, amikacin and gentamycin (92.5%) was most effective in hospital C, and nitrofurantoin in hospital A (78%). The second commonest organism, i.e., S. aureus (23%) was most sensitive to cephalosporin (88.8%) of second generation, followed by nitrofurantoin (77.7%), amikacin (80.6%) and norfloxacin (65.5%). The third common organism, Klebsiella (9.71%) was most sensitive to norfloxacin (75%) and nitrofurantoin (75%). Lastly, Pseudomonas was resistant to all the antibiotics in hospital A, D and E, nil in hospital B and sensitive to amikacin (100%) in hospital C. Keywords: UTI, common pathogens, antibiotics sensitivity, resistance profile | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/319 | |
| dc.language.iso | en_US | |
| dc.publisher | Kathmandu University | |
| dc.title | A study of sensitivity and resistance of pathogenic micro organisms causing UTI in Kathmandu valley | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Original Article | |
| oaire.citation.endPage | 129 | |
| oaire.citation.startPage | 123 | |
| relation.isJournalIssueOfPublication | dc8d6075-0695-4e05-bd4b-b6d66c9cf3da | |
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