Publication:
Bulbar Onset Amyotrophic Lateral Sclerosis: A Case Report

Date

2023

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Nepal Medical Association

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Abstract

Abstract Amyotrophic lateral sclerosis is a rare, progressive, incurable neurodegenerative disorder that affects motor neurons leading to progressive muscle weakness, disability, and eventually death. A 45-year-old male, initially presented with hoarseness, flickering of tongue, and intermittent aspirations. In course of three years, patient developed motor aphasia, frequent aspirations and an inability to hold his neck. Patient was diagnosed with a bulbar onset type of amyotrophic lateral sclerosis on the basis of neurodegenerative features with normal radiographic imaging. For the prevention of recurrent aspiration pneumonia, he was managed with a percutaneous endoscopic gastrostomy tube. As he started developing respiratory failure tracheostomy was performed and kept on a continuous bi-level positive airway pressure ventilator, in the meantime, two courses of injection Edaravone were given. Early evaluation, diagnosis and management of the condition is a cornerstone for better prognosis of disease and survival.

Description

Kabindra Rai KIST Medical College and Teaching Hospital, Mahalaxmi, Lalitpur, Nepal Nilshan Rai KIST Medical College and Teaching Hospital, Mahalaxmi, Lalitpur, Nepal Milan Kumar Chhantel Thapa KIST Medical College and Teaching Hospital, Mahalaxmi, Lalitpur, Nepal Rajan Shrestha KIST Medical College and Teaching Hospital, Mahalaxmi, Lalitpur, Nepal Sampurna Singh KIST Medical College and Teaching Hospital, Mahalaxmi, Lalitpur, Nepal Monika Thapa Department of Neurology, National Neuro Center, Maharajgunj, Kathmandu, Nepal

Keywords

amyotrophic lateral sclerosis, aspiration Pneumonia, Case reports, Edaravone

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