Publication:
Bulbar Onset Amyotrophic Lateral Sclerosis: A Case Report

creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorRai, Kabindra
dc.contributor.authorRai, Nilshan
dc.contributor.authorThapa, Milan Kumar Chhantel
dc.contributor.authorShrestha, Rajan
dc.contributor.authorSingh, Sampurna
dc.contributor.authorThapa, Monika
dc.date.accessioned2025-09-28T06:56:10Z
dc.date.available2025-09-28T06:56:10Z
dc.date.issued2023
dc.descriptionKabindra Rai KIST Medical College and Teaching Hospital, Mahalaxmi, Lalitpur, Nepal Nilshan Rai KIST Medical College and Teaching Hospital, Mahalaxmi, Lalitpur, Nepal Milan Kumar Chhantel Thapa KIST Medical College and Teaching Hospital, Mahalaxmi, Lalitpur, Nepal Rajan Shrestha KIST Medical College and Teaching Hospital, Mahalaxmi, Lalitpur, Nepal Sampurna Singh KIST Medical College and Teaching Hospital, Mahalaxmi, Lalitpur, Nepal Monika Thapa Department of Neurology, National Neuro Center, Maharajgunj, Kathmandu, Nepal
dc.description.abstractAbstract Amyotrophic lateral sclerosis is a rare, progressive, incurable neurodegenerative disorder that affects motor neurons leading to progressive muscle weakness, disability, and eventually death. A 45-year-old male, initially presented with hoarseness, flickering of tongue, and intermittent aspirations. In course of three years, patient developed motor aphasia, frequent aspirations and an inability to hold his neck. Patient was diagnosed with a bulbar onset type of amyotrophic lateral sclerosis on the basis of neurodegenerative features with normal radiographic imaging. For the prevention of recurrent aspiration pneumonia, he was managed with a percutaneous endoscopic gastrostomy tube. As he started developing respiratory failure tracheostomy was performed and kept on a continuous bi-level positive airway pressure ventilator, in the meantime, two courses of injection Edaravone were given. Early evaluation, diagnosis and management of the condition is a cornerstone for better prognosis of disease and survival.
dc.identifierhttps://doi.org/10.31729/jnma.8098
dc.identifier.urihttps://hdl.handle.net/20.500.14572/2426
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.subjectamyotrophic lateral sclerosis
dc.subjectaspiration Pneumonia
dc.subjectCase reports
dc.subjectEdaravone
dc.titleBulbar Onset Amyotrophic Lateral Sclerosis: A Case Report
dc.typeOther
dspace.entity.typePublication
local.article.typeCase Report
oaire.citation.endPage273
oaire.citation.startPage271
relation.isJournalIssueOfPublication1a48971b-f01c-4cb6-9e15-badb9467396e
relation.isJournalIssueOfPublication.latestForDiscovery1a48971b-f01c-4cb6-9e15-badb9467396e
relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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