Publication: Comparison of Oral Trichlophos and Intranasal Midazolam for Sedation in Minimally Invasive Paediatric Procedures (RAMT Study)
| creativeworkseries.issn | ISSN 1990-7974 eISSN 1990-7982 | |
| dc.contributor.author | Sharma, Manoj | |
| dc.contributor.author | Yenamandra, Kamal K. | |
| dc.contributor.author | Kalita, Jitu | |
| dc.contributor.author | Dash, Shaswat | |
| dc.contributor.author | Singh, Daljit | |
| dc.date.accessioned | 2026-01-13T09:37:19Z | |
| dc.date.available | 2026-01-13T09:37:19Z | |
| dc.date.issued | 2018 | |
| dc.description | Manoj Sharma Military Hospital Jammu Kamal K. Yenamandra Command Hospital Air Force Bangalore, India Jitu Kalita 7 Air Force Hospital Kanpur, India Shaswat Dash 5 Air Force Hospital Jorhat, India Daljit Singh Command Hospital Air Force, Bangalore, India | |
| dc.description.abstract | Abstract: Introduction: Uncooperative child does not allow completion of procedures, denying valuable data required for clinicians. Material and Methods: An open labelled parallel group prospective randomized control study was conducted at zonal hospital Jorhat. We evaluated 200 children randomized into two groups using computer based randomization. Participants aged 3 months to 5 years (n=200) were randomized to receive 50 mg/kg Triclofos sodium orally or intranasal spray of midazolam 0.2 mg/kg. Results: Adequate sedation (Ramsay reactivity score of 3 and 4) was obtained in 86% children in midazolam group as compared to 80% in triclofos group with p value of 0.138. Mean duration for onset of sedation was 20 min ± 5.4 min in Trichlophos group and 12 min ± 4.5 min with Intranasal Midazolam which was statistically significant with p-value of <0.001. The mean duration of post procedural sedation was found to be 24.00 ± 9.21 min in midazolam group and 49.00 ± 16.99 min in triclofos group (p=<0.001) which was statistically significant. No significant difference was seen for side effects frequency between the two drugs (15% in Triclofos, 10% in Midazolam group; p=0.285). Conclusion: We conclude that intranasal midazolam is more effective than oral trichlophos with a comparable safety profile. | |
| dc.identifier | https://doi.org/10.3126/jnps.v38i2.19139 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/4229 | |
| dc.language.iso | en_US | |
| dc.publisher | Nepal Paediatric Society (JNPS) | |
| dc.subject | Trichlophos | |
| dc.subject | Midazolam | |
| dc.subject | Sedation | |
| dc.subject | Ramsay score | |
| dc.title | Comparison of Oral Trichlophos and Intranasal Midazolam for Sedation in Minimally Invasive Paediatric Procedures (RAMT Study) | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Original Article | |
| oaire.citation.endPage | 83 | |
| oaire.citation.startPage | 80 | |
| relation.isJournalIssueOfPublication | c350fd58-9e5b-48f5-87a2-b9e0c3cf4626 | |
| relation.isJournalIssueOfPublication.latestForDiscovery | c350fd58-9e5b-48f5-87a2-b9e0c3cf4626 | |
| relation.isJournalOfPublication | 6f9be05c-05a9-4a3e-a5b5-a19a15ab042c |