Publication:
Recurrent Metastatic Choriocarcinoma Responsive to Etoposide and Cisplatin with Etoposide, Methotrexate, and Dactinomycin: A Case Report

creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorDas, Sunil Kumar
dc.contributor.authorShahi, Arun
dc.contributor.authorPanthi, Ram Chandra
dc.date.accessioned2025-12-17T09:13:27Z
dc.date.available2025-12-17T09:13:27Z
dc.date.issued2022
dc.descriptionSunil Kumar Das Department of General Practice and Emergency Medicine, Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal https://orcid.org/0000-0002-6568-5149 Arun Shahi Department of Oncology, Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal Ram Chandra Panthi Department of Internal Medicine, Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal
dc.description.abstractAbstract Choriocarcinoma is a malignant trophoblastic tumour usually of placental origin. It is characterized by early metastasis to the brain and lungs. With early detection, it has a better prognosis with treatment. We report a case of 18 years female at 26 weeks of gestation in her third pregnancy who had a history of treatment for metastatic gestational trophoblastic neoplasm with chemotherapy and radiotherapy two years back. Therefore, she was managed as a case of recurrent choriocarcinoma with brain metastasis with chemotherapy (etoposide and cisplatin with etoposide, methotrexate, and dactinomycin) and was responsive. Her symptoms resolved and β-human chorionic gonadotropin dropped to normal value (<2.39 mIU/ml) which has shown that timely diagnosis and management can be vital for the successful treatment of brain metastasis.
dc.identifierhttps://doi.org/10.31729/jnma.7081
dc.identifier.urihttps://hdl.handle.net/20.500.14572/3673
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.subjectChemotherapy
dc.subjectChoriocarcinoma
dc.subjectMetastasis
dc.subjectRecurrence
dc.titleRecurrent Metastatic Choriocarcinoma Responsive to Etoposide and Cisplatin with Etoposide, Methotrexate, and Dactinomycin: A Case Report
dc.typeOther
dspace.entity.typePublication
local.article.typeCase Report
oaire.citation.endPage490
oaire.citation.startPage488
relation.isJournalIssueOfPublication90280378-78a5-4d2f-8cf6-3e00c8a07c12
relation.isJournalIssueOfPublication.latestForDiscovery90280378-78a5-4d2f-8cf6-3e00c8a07c12
relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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