Publication: Recurrent Metastatic Choriocarcinoma Responsive to Etoposide and Cisplatin with Etoposide, Methotrexate, and Dactinomycin: A Case Report
Date
2022
Article Type
Case Report
Journal Title
Journal ISSN
JNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
Volume Title
Pages
Pages: 488 - 490
Publisher
Nepal Medical Association
Abstract
Abstract
Choriocarcinoma is a malignant trophoblastic tumour usually of placental origin. It is characterized by early metastasis to the brain and lungs. With early detection, it has a better prognosis with treatment. We report a case of 18 years female at 26 weeks of gestation in her third pregnancy who had a history of treatment for metastatic gestational trophoblastic neoplasm with chemotherapy and radiotherapy two years back. Therefore, she was managed as a case of recurrent choriocarcinoma with brain metastasis with chemotherapy (etoposide and cisplatin with etoposide, methotrexate, and dactinomycin) and was responsive. Her symptoms resolved and β-human chorionic gonadotropin dropped to normal value (<2.39 mIU/ml) which has shown that timely diagnosis and management can be vital for the successful treatment of brain metastasis.
Description
Sunil Kumar Das
Department of General Practice and Emergency Medicine, Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal
https://orcid.org/0000-0002-6568-5149
Arun Shahi
Department of Oncology, Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal
Ram Chandra Panthi
Department of Internal Medicine, Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal
Keywords
Chemotherapy, Choriocarcinoma, Metastasis, Recurrence
Identifier
https://doi.org/10.31729/jnma.7081