Publication:
Histopathological Analysis of Non-Neoplastic Superficial Lymphadenopathies

creativeworkseries.issn1812-2027
dc.contributor.authorThapa, S
dc.contributor.authorGhosh, A
dc.contributor.authorGhartimagar, D
dc.contributor.authorNarasimhan, R
dc.contributor.authorPrasad, T
dc.contributor.authorTalwar, OP
dc.date.accessioned2025-10-28T06:33:47Z
dc.date.available2025-10-28T06:33:47Z
dc.date.issued2017
dc.descriptionThapa S, Ghosh A, Ghartimagar D, Narasimhan R, Prasad T, Talwar OP Department of Pathology Manipal Teaching Hospital Manipal College of Medical Sciences Pokhara, Nepal
dc.description.abstractABSTRACT Background Lymphadenopathies are the clinical manifestation of enlargement of lymph nodes which are a common occurrence and are processes of lymph nodes in response to a variety of exogenous and endogenous stimulants. The vast majority of enlarged lymph nodes are non-neoplastic. Objective The objective of the study is to analyze the spectrum of non-neoplastic lesions of superficial lymphadenopathies with their histomorphological features. Method This was a retrospective hospital based study done in the department of Pathology. All cases of superficial lymph node biopsies received during a period of 7 years were retrieved and divided into 2 broad categories: neoplastic and non-neoplastic. The latter group is the material for the present study. The diagnosis was made on morphological basis. Result Of all the 268 superficial lymph node biopsies, 25.4% (68 cases) were neoplastic and 74.6% (200 cases) were non-neoplastic. The non-neoplastic cases were further categorized into non-infectious 60.5% (121 cases) and infectious 39.5% (79 cases). Neck node (70%) was the most common site of involvement. There were 102 male and 98 female patients with male to female ratio 1.04:1. The age range of the patients was 2 years to 83 years with a mean of 27.16 years and most common being 11-20 years 29% (58 cases). Majority of the cases were non-specific reactive lymphadenitis 84.3% (102 cases) followed by tuberculosis 36.5% (73 cases). Conclusion The major cause for the superficial lymphadenopathy was found to be non- neoplastic etiology with slight male predominance. Reactive lymphadenitis was the leading cause unlike the studies done in other Asian and Tropical countries where tuberculosis was more common. KEY WORDS Lymphadenopathies, non-neoplastic, reactive lymphadenitis, tuberculosis
dc.identifier.urihttps://hdl.handle.net/20.500.14572/2837
dc.language.isoen_US
dc.publisherKathmandu University
dc.subjectLymphadenopathies
dc.subjectnon-neoplastic
dc.subjectreactive lymphadenitis
dc.subjecttuberculosis
dc.titleHistopathological Analysis of Non-Neoplastic Superficial Lymphadenopathies
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage55
oaire.citation.startPage50
relation.isJournalIssueOfPublication5b639290-8330-4777-94d5-c27def556395
relation.isJournalIssueOfPublication.latestForDiscovery5b639290-8330-4777-94d5-c27def556395
relation.isJournalOfPublicationa782b7ff-cf89-4178-ad1c-11ed89cfe1bd

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