Publication: Pseudomonas aeruginosa Isolates among Clinical Samples showing Growth in a Tertiary Care Centre: A Descriptive Cross-sectional Study
| creativeworkseries.issn | JNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X | |
| dc.contributor.author | Maharjan, Nabina | |
| dc.date.accessioned | 2025-12-01T08:37:08Z | |
| dc.date.available | 2025-12-01T08:37:08Z | |
| dc.date.issued | 2022 | |
| dc.description | Nabina Maharjan Department of Microbiology, Lumbini Medical College and Teaching Hospital, Tansen, Palpa, Nepal | |
| dc.description.abstract | Abstract Introduction: Carbapenems resistance due to metallo-beta-lactamase production in Pseudomonas aeruginosa is a major concern which is increasing globally resulting in limited therapeutic choices. This study aimed to find out the prevalence of Pseudomonas aeruginosa isolates among clinical samples showing growth of a tertiary care centre. Methods: A descriptive cross-sectional study was conducted on various clinical samples which showed growth in the Department of Microbiology of a tertiary care centre between 1 September 2020 to 28 February 2021 after receiving ethical approval from the Institutional Review Committee (Reference number: 03-G/020). Convenience sampling was done. All timely received clinical specimens were inoculated and incubated at 37°C for 48 hours and identified by standard microbiological techniques. Point estimate and 95% Confidence Interval were calculated. Results: Among 1049 clinical samples showing growth, 68 (6.48%) (4.99-7.97, 95% Confidence Interval) Pseudomonas aeruginosa were isolated. Among them, 6 (8.82%) were found to be metallo-beta-lactamase positive. Conclusions: The prevalence of Pseudomonas aeruginosa was similar to the studies done in similar settings. As metallo-beta-lactamase production was detected among isolated species which can be spread very rapidly and may develop a problematic scenario in treatment procedures, regular surveillance along with judicious use of carbapenems should precede. | |
| dc.identifier | https://doi.org/10.31729/jnma.6517 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/3342 | |
| dc.language.iso | en_US | |
| dc.publisher | Nepal Medical Association | |
| dc.subject | Beta-lactamase | |
| dc.subject | Multidrug resistant | |
| dc.subject | Pseudomonas aeruginosa | |
| dc.title | Pseudomonas aeruginosa Isolates among Clinical Samples showing Growth in a Tertiary Care Centre: A Descriptive Cross-sectional Study | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Original Article | |
| oaire.citation.endPage | 680 | |
| oaire.citation.startPage | 676 | |
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