Publication: Gastric Neoplasm: A Clinicopathological Study in the Tertiary Care Center of Nepal
Date
2024
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Background
Gastric carcinoma is the commonest upper gastrointestinal malignancy contributing
to global burden of cancer morbidity and mortality.
Objective
The objective is to study distribution of the gastric neoplasm according to age, sex,
symptom, gross appearance, histological type and degree of differentiation.
Method
This was a retrospective study done from January 2022 to December 2023 in the
Department of Pathology, Dhulikhel Hospital - Kathmandu University Hospital (DH -
KUH). Relevant clinical data of the patients were obtained from the histopathological
records of the patient from the pathology department and biopsies stained with
Haematoxylin and Eosin were studied under the light microscope.
Result
A total of 40 cases of gastric neoplasm were studied out of which 36(90%) were
malignant and 4(10%) were benign epithelial tumors and precursor lesions. Most
frequent presentation was dyspepsia, abdominal pain, vomiting, dysphagia, anemia,
anorexia and weight loss. Male to female ratio was 1.4:1. The age of the patient
ranged from 33 to 89 years with mean age of 63.3 ± 13.4 years. Most common
site of gastric neoplasm was pyloric antrum. Ulceroproliferative growth was most
common gross morphology. Malignant neoplasm were more common. Intestinal
type adenocarcinoma consisted of 28 (70%) cases followed by diffuse type 6 (15%)
and mixed type 1 (2.5%). Diffuse adenocarcinoma was more common in females.
Moderately differentiated adenocarcinoma was the most common differentiation.
Conclusion
The present study provided a fair insight into the clinciopathological features of
gastric neooplasm in our institution.
KEY WORDS
Adenocarcinoma, Diffuse type, Gastric, Intestinal type
Description
Basnet D,1 Makaju R,1 Gurung RB,2 Gautam N,1 Shrestha B,1 Maharjan PB,1 KC P1
1Department of Pathology
2Department of Internal Medicine
Dhulikhel Hospital, Kathmandu University Hospital
Kathmandu University School of Medical Sciences
Dhulikhel, Kavre, Nepal
Keywords
Adenocarcinoma, Diffuse type, Gastric, Intestinal type