Publication:
Role of Tranexamic acid in NSAIDS induced angioedema

creativeworkseries.issnISSN 2822-1893 eISSN 2822-2016
dc.contributor.authorChalise, Rupak
dc.contributor.authorPoudel, Saroj
dc.contributor.authorBist, Manoj
dc.contributor.authorRegmi, Ashim
dc.contributor.authorGhimire, Anup
dc.contributor.authorKhanal, Kishor
dc.date.accessioned2026-02-03T05:08:57Z
dc.date.available2026-02-03T05:08:57Z
dc.date.issued2023
dc.descriptionRupak Chalise Department of Critical Care Medicine, Nepal Mediciti Hospital Saroj Poudel Department of Critical Care Medicine, Nepal Mediciti Hospital Manoj Bist Department of Critical Care Medicine, Nepal Mediciti Hospital Ashim Regmi Department of Critical Care Medicine, Nepal Mediciti Hospital Anup Ghimire Department of Critical Care Medicine, Nepal Mediciti Hospital Kishor Khanal Department of Critical Care Medicine, Nepal Mediciti Hospital
dc.description.abstractAbstract: Tranexamic acid (TXA) is an antifibrinolytic agent that inhibits the conversion of plasminogen to plasmin, a key step in kallikrein activation and bradykinin formation. Tranexamic acid is used in the prophylactic management of hereditary angioedema; however, evidence for TXA in Non-Steroidal Anti-inflammatory drug-induced angioedema (NSAIDS-AE) is limited. We describe a patient who presented to the ICU department with NSAIDS-AE and was successfully treated with TXA. This case suggests that TXA may be a beneficial treatment modality in the management of NSAIDS-AE and warrants further investigation.
dc.identifierhttps://doi.org/10.3126/nrj.v2i1.59613
dc.identifier.urihttps://hdl.handle.net/20.500.14572/4464
dc.language.isoen_US
dc.publisherNepalese Respiratory Society
dc.subjectAnaphylaxis
dc.subjectNon-allergic Anaphylaxis
dc.subjectTranexamic acid
dc.subjectAngioedema
dc.titleRole of Tranexamic acid in NSAIDS induced angioedema
dc.typeArticle
dspace.entity.typePublication
local.article.typeCase Report
oaire.citation.endPage33
oaire.citation.startPage31
relation.isJournalIssueOfPublication26e8be9d-ae5a-47a4-aadf-32b534668084
relation.isJournalIssueOfPublication.latestForDiscovery26e8be9d-ae5a-47a4-aadf-32b534668084
relation.isJournalOfPublication91ea7cc8-46b2-4796-94bd-2998c28b5ebb

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