Publication: Sensitivity and Specificity of Nepali Version of Quantitative Androgen Deficiency in Aging Males (qADAM) Questionnaire in Diabetic Patients
Date
2023
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Background
Diabetes mellitus (DM) is a chronic disorder with hyperglycemia that affects multiple
systems with hypogonadism and erectile dysfunction some common issues affecting
their quality sexual life. Quantitative androgen deficiency in aging males (qADAM)
questionnaire is a trusted tool to assess hypogonadism and erectile dysfunction
among diabetic patients and has been commonly used in Nepal too. However, the
accuracy, sensitivity, and specificity of its Nepali version are yet to be tested.
Objective
To assess the accuracy, sensitivity, and specificity of the Nepali version of the
quantitative androgen deficiency in aging males questionnaire among diabetic
patients.
Method
A cross-sectional study was conducted among diabetic patients attending Dhulikhel
Hospital, Kathmandu University Hospital. The Patients were asked to complete the
valid Nepali translated version of quantitative Androgen Deficiency in Aging Males
questionnaire. Participants’ serum total and free testosterone, lipid profile, fasting
blood glucose, HbA1c and Sex Hormone Binding Globulin (SHBG) were measured in
clinical biochemistry laboratory and the accuracy, sensitivity and specificity of Nepali
version of quantitative androgen deficiency in aging males were analyzed.
Result
The translated Nepali version of quantitative androgen deficiency in aging males
questionnaire showed 61.9% sensitivity, 45.5% specificity, and 56.7% accuracy in
diagnosing hypogonadism in reference to serum testosterone level.
Conclusion
This Nepali translated version of quantitative androgen deficiency in aging males
questionnaire can be a noninvasive tool to assess hypogonadism and erectile
dysfunction.
KEY WORDS
Diabetes, Hypogonadism, Nepali Translation, Quantitative androgen deficiency in
aging males
Description
Bhatt RD,1,3 Risal P,1 Maharjan A,1 Timalsina D,2 Qiqiang HE3
1Department of Clinical Biochemistry
2Department of Community Program
Dhulikhel Hospital, Kathmandu University Hospital
Kathmandu University School of Medical Science
Dhulikhel, Kavre, Nepal
3Wuhan University
Faculty of Medical Sciences, School of Public Health
China
Keywords
Diabetes, Hypogonadism, Nepali Translation, Quantitative androgen deficiency in aging males