Publication:
Terbinafine-induced Toxic Epidermal Necrolysis in Pregnancy: A Case Report

Date

2023

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Publisher

Nepal Medical Association

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Abstract

Abstract Toxic epidermal necrolysis in pregnancy is a rare disease that can have an adverse effect on Toxic epidermal necrolysis in pregnancy is a rare disease that can have an adverse effect on pregnancy outcomes. Common etiology of the condition includes medication triggered followed by mycoplasma infection. Almost one-third of cases are idiopathic. Despite the rarity of data, terbinafine causing toxic epidermal necrolysis has been reported. Toxic epidermal necrolysis manifests as a macule, erythema followed by a blister in the chest and spreading to other parts of the body. Removal of the offending agent and supportive management is the cornerstone of management. Here we report 22-year-old primipara pregnant women presenting with toxic epidermal necrolysis after 3 weeks of oral terbinafine use with good pregnancy outcomes.

Description

Ramesh Lamichhane Department of Internal Medicine, Nepal Cardio Diabetes and Thyroid Center, Budhanilkantha, Kathmandu, Nepal Mahendra Raj Pandey Department of Dermatology, National Medical College and Teaching Hospital, Bhediyahi, Birgunj, Nepal Ayushma Dhungana Department of Dermatology, National Medical College and Teaching Hospital, Bhediyahi, Birgunj, Nepal Anjana Lamsal Department of Dermatology, National Medical College and Teaching Hospital, Bhediyahi, Birgunj, Nepal

Keywords

Case reports, Pregnancy, Stevens-Johnson syndrome, Toxic epidermal necrolysis

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