Publication:
Hypothyroidism among Type 2 Diabetic Patients Visiting Outpatient Department of Internal Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study

creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorShrestha, Biju
dc.contributor.authorRai, Chandra Kala
dc.date.accessioned2025-09-26T05:40:57Z
dc.date.available2025-09-26T05:40:57Z
dc.date.issued2023
dc.descriptionBiju Shrestha Department of Physiology, Kathmandu Medical College and Teaching Hospital, Duwakot, Bhaktapur, Nepal Chandra Kala Rai Department of Physiology, Kathmandu Medical College and Teaching Hospital, Duwakot, Bhaktapur, Nepal
dc.description.abstractAbstract Introduction: Diabetes-thyroid relationship is said to be bidirectional. Insulin resistance and hyperinsulinemia in type 2 diabetes mellitus increase free thyroxine but decrease free tri-iodothyronine and thyroid-releasing hormone synthesis. Thyroid dysfunction may in turn impose an adverse effect on glucose metabolism in type 2 diabetes mellitus. Undetected thyroid dysfunction can worsen glycemic control and predispose type 2 diabetes mellitus patients to cardiovascular and other diabetes-related complications. Recognition and timely treatment of thyroid dysfunction in type 2 diabetes mellitus patients can delay diabetic complications. The aim of this study was to find out the prevalence of hypothyroidism among type 2 diabetic patients visiting the outpatient Department of Internal Medicine of a tertiary care centre. Methods: A descriptive cross-sectional study was conducted from 17 April 2021 to 5 September 2021 after obtaining ethical approval from the Institutional Review Committee (Reference number: 130120202). A total of 384 type 2 diabetic subjects were recruited for the study. Convenience sampling method was used. Point estimate and 95% CI were calculated. Results: Among 384 patients, the prevalence of hypothyroidism was found in 127 (33.07%) (28.36-37.78, 95% Confidence Interval). Among them, 56 (44.09%) were male and 71 (55.90%) were female. The mean age was 55.17±7.53 years. Conclusions: The prevalence of hypothyroidism was higher than in the other studies done in similar settings.
dc.identifierhttps://doi.org/10.31729/jnma.8130
dc.identifier.urihttps://hdl.handle.net/20.500.14572/2386
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.subjectPrevalence
dc.subjectThyroid dysfunction
dc.subjectType 2 diabetes mellitus
dc.titleHypothyroidism among Type 2 Diabetic Patients Visiting Outpatient Department of Internal Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage328
oaire.citation.startPage325
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relation.isJournalIssueOfPublication.latestForDiscoverycb29f96c-a94f-4864-95b6-9f7f36256766
relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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