Publication: Hypothyroidism among Type 2 Diabetic Patients Visiting Outpatient Department of Internal Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study
Date
2023
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract
Introduction: Diabetes-thyroid relationship is said to be bidirectional. Insulin resistance and hyperinsulinemia in type 2 diabetes mellitus increase free thyroxine but decrease free tri-iodothyronine and thyroid-releasing hormone synthesis. Thyroid dysfunction may in turn impose an adverse effect on glucose metabolism in type 2 diabetes mellitus. Undetected thyroid dysfunction can worsen glycemic control and predispose type 2 diabetes mellitus patients to cardiovascular and other diabetes-related complications. Recognition and timely treatment of thyroid dysfunction in type 2 diabetes mellitus patients can delay diabetic complications. The aim of this study was to find out the prevalence of hypothyroidism among type 2 diabetic patients visiting the outpatient Department of Internal Medicine of a tertiary care centre.
Methods: A descriptive cross-sectional study was conducted from 17 April 2021 to 5 September 2021 after obtaining ethical approval from the Institutional Review Committee (Reference number: 130120202). A total of 384 type 2 diabetic subjects were recruited for the study. Convenience sampling method was used. Point estimate and 95% CI were calculated.
Results: Among 384 patients, the prevalence of hypothyroidism was found in 127 (33.07%) (28.36-37.78, 95% Confidence Interval). Among them, 56 (44.09%) were male and 71 (55.90%) were female. The mean age was 55.17±7.53 years.
Conclusions: The prevalence of hypothyroidism was higher than in the other studies done in similar settings.
Description
Biju Shrestha
Department of Physiology, Kathmandu Medical College and Teaching Hospital, Duwakot, Bhaktapur, Nepal
Chandra Kala Rai
Department of Physiology, Kathmandu Medical College and Teaching Hospital, Duwakot, Bhaktapur, Nepal
Keywords
Prevalence, Thyroid dysfunction, Type 2 diabetes mellitus