Publication:
Clinical Response to Amoxicillin among Children with Acute Suppurative Otitis Media

Simple item page
creativeworkseries.issn1999-6217
dc.contributor.authorJoshi, Deepa
dc.contributor.authorNepal, Ajit
dc.contributor.authorShrestha, Namita
dc.contributor.authorRajbhandari, Piyush
dc.contributor.authorBagale, Gyanendra
dc.contributor.authorChapagain, Saroj
dc.contributor.authorDhakal, Srijana
dc.date.accessioned2026-09-10T09:48:50Z
dc.date.available2026-09-10T09:48:50Z
dc.date.issued2025
dc.descriptionDeepa Joshi Department of ENT and HNS, Bir hospital, NAMS, Kathmandu. Ajit Nepal Department of ENT and HNS, Patan Academy of Health Sciences, Lalitpur, Nepal. Namita Shrestha Department of ENT and HNS, Patan Academy of Health Sciences, Lalitpur, Nepal. Piyush Rajbhandari Department of Microbiology, Patan Academy of Health Sciences, Lalitpur, Nepal. Gyanendra Bagale Department of ENT and HNS, Patan Academy of Health Sciences, Lalitpur, Nepal. Saroj Chapagain Department of ENT and HNS, Patan Academy of Health Sciences, Lalitpur, Nepal. Srijana Dhakal Department of ENT and HNS, Patan Academy of Health Sciences, Lalitpur, Nepal.
dc.description.abstractAbstract: Background: Acute Suppurative Otitis Media(ASOM) is a very common disease of childhood caused by various bacteria and viruses. Amoxicillin is used as first line antibiotics in the community setting as well as hospital setting. Methods: This is a hospital based prospective observational cross-sectional study. All cases of ASOM of patients under 14 years presenting to the Patan Hospital with duration of less than 6weeks were included in the study. Ear discharge was collected using sterile cotton swab using aseptic precautions and sent to the Department of Microbiology for further processing. The children were treated with amoxicillin (80mg/kg/day) with maximum dose not exceeding 3g/day and follow up was done after 1 week of antibiotic therapy for clinical responsiveness. Results: Out of 32 cases, 13 cases showed no growth of organism in the culture sensitivity reports. Among remaining 19 cases, 9 were sensitive and 10 were resistant to amoxicillin. Coagulase negative Staphylococcus (7) was the most common organism grown in the laboratory followed by Staphylococcus aureus (4) and Klebsiella pneumoniae (4). Chloramphenicol, linezolid, clindamycin and trimethoprim-sulphamethoxazole were the most common antibiotics sensitive to the organisms grown besides amoxicillin. Out of total 32 patients, 31 were responsive to high dose amoxicillin at the end of 1 week. Conclusions: Oral amoxicillin in high doses is effective in the treatment of ASOM in children.
dc.identifierhttps://doi.org/10.33314/jnhrc.v23i02.4861
dc.identifier.urihttps://hdl.handle.net/20.500.14572/7630
dc.language.isoen_US
dc.publisherNepal Health Research Council
dc.subjectASOM
dc.subjectCclinical response
dc.subjectHigh dose amoxicillin
dc.titleClinical Response to Amoxicillin among Children with Acute Suppurative Otitis Media
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage268
oaire.citation.startPage263
relation.isJournalIssueOfPublication5df7ea21-413e-4c7e-92f6-f85d6e7a64ef
relation.isJournalIssueOfPublication.latestForDiscovery5df7ea21-413e-4c7e-92f6-f85d6e7a64ef
relation.isJournalOfPublication40bd2739-8b19-447c-be60-723a1bdd1dcd

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
263-268.pdf
Size:
276.85 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.86 KB
Format:
Item-specific license agreed to upon submission
Description:
Download

Collections

Publications

Connect with us

Nepal Health Research Council © 2026
Ramshah Path, Kathmandu Nepal P.O.Box 7626