Publication:
Panniculitis in Anti-MDA-5 Positive Juvenile Dermatomyositis: A Case Report

Date

2025

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Nepal Medical Association

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Abstract Panniculitis is a rare clinical finding in dermatomyositis. There are few reported cases in the medical literature. In this report, we describe a 17-year-old male patient with anti-MDA5 positive hypomyopathic dermatomyositis who, eight months after diagnosis, presented with indurated nodules on the right forearm and right thigh despite methotrexate and monthly intravenous immunoglobulin treatment. A skin biopsy revealed lobular panniculitis with lymphocytic infiltrate. His lesions were successfully controlled with hydroxychloroquine and azathioprine. This article presents a case regarding the rarity of panniculitis in juvenile dermatomyositis and its treatment strategy.

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Semra Ayduran Department of Pediatric Rheumatology, Pamukkale University, Denizli, Turkiye Gulsah Kilbas Department of Pediatric Rheumatology, Pamukkale University, Denizli, Turkiye Saadet Nilay Tigrak Department of Pediatric Rheumatology, Pamukkale University, Denizli, Turkiye Selcuk Yuksel Department of Pediatric Rheumatology, Canakkale Onsekiz Mart University, Canakkale, Turkiye Erdem Comut Department of Pathology, Pamukkale University, Pathology, Denizli, Turkiye Serkan Turkucar Department of Pediatric Rheumatology, Pamukkale University, Denizli, Turkiye

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