Publication: Comparison of PAP test among high and non-high risk female
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Date
2003
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Kathmandu University
Abstract
prospective study of pap smear in 100 high risk and equal number of non high risk female among total
1022 female Gynecological patients within a period of two and half months {Beginning of Sept. to middle of Nov.
1995} in Maternity Hospital, Thapathali is presented. There were 9 cases positive for dyskaryosis among high risk
and 3 cases among the comparison group. All positive cases were at the age of 35 years and above. In 9 positive
cases, 5 cases were in CIN I (55.55%) while 4 were in CIN II (44.44%). Similarly out of 3 positive cases in
comparison group 1 was in CIN I category (33.33%) and 2 cases were in CIN II (66.66%). Relation of positive cases
with low social class revealed 80% CIN I and 50% CIN II among high risk group where as 66.6% CIN II in
comparison group. Analysis of risk factor in development of various grades Dyskaryosis revealed 60% of CIN I had
high parity while 50% had CIN II. There are about 40% of CIN I and 75% CIN II among child birth < 19yrs, 60%
smoker had CIN I where as 100%. Smoker had CIN II. 80% of CIN I gave history of excessive vaginal discharge
where as 50% of CIN II had excessive vaginal discharge. 40% of CIN I was having injection Depo provera. Cases
were also analyzed according to risk factor. Out of 9 positive cases among high-risk females 5 positive had parity
more than 4 and 4 cases had less than 4. 5 positive cases were among less than 19 years of first childbirth, 4 among
more than 19 years. 7 positive cases were smoker and 2 positive cases were non-smoker. 6 positive cases gave
history of abnormal vaginal discharge and 3 positive cases had no abnormal vaginal discharge. Out of 9 positive
cases 2 had history of injection Depo provera continuously for >5 years where as 7 were non users.
Key words: PAP Smear, High risk, Dyskaryosis, CIN