Publication: Rhino-Orbital Mucormycosis in a COVID-19 Patient: A Dreadful Challenge
Date
2022
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Coronavirus disease 2019 (COVID-19) is a pandemic disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-COV-2). COVID-19 infections
may be associated with a wide range of bacterial and fungal co-infections. Recent
studies are reporting invasive fungal infection associated with severe COVID-19.
Herein, we report a case of COVID-19 rhino-orbital mucormycosis infection caused
by Rhizopus sps in a 32 year old diabetic patient who was successfully managed
with early aggressive debridement of infected tissue endoscopically with extended
ethmoidectomy by modified Denker’s approach along with orbital decompression
and antifungal therapy with Liposomal Amphotericin B and Posaconazole. Serial
diagnostic nasal endoscopy showed no evidence of progression of the infection.
The patient was discharged on 21st day of hospitalization still on oral Posaconazole
for a total of 3 months.
KEY WORDS
Amphotericin B, Covid-19, Mucormycosis, Surgical debridement
Description
Dhakal A, Pokharel M, Madhup S, Khadka L, Sapkota B
Department of ENT-HNS
Dhulikhel Hospital, Kathmandu University Hospital
Dhulikhel, Kavre, Nepal
Keywords
Amphotericin B, Covid-19, Mucormycosis, Surgical debridement