Publication:
Clinico-Pathological Correlation of Colorectal Diseases by Colonoscopy and Biopsy

creativeworkseries.issn1812-2027
dc.contributor.authorMakaju, R
dc.contributor.authorAmatya, M
dc.contributor.authorSharma, S
dc.contributor.authorDhakal, R
dc.contributor.authorBhandari, S
dc.contributor.authorShrestha, S
dc.contributor.authorGurung, R
dc.contributor.authorMalla, BR
dc.date.accessioned2025-10-29T06:22:12Z
dc.date.available2025-10-29T06:22:12Z
dc.date.issued2017
dc.descriptionMakaju R,1 Amatya M,1 Sharma S,1 Dhakal R,1 Bhandari S,1 Shrestha S,1 Gurung R,2 Malla BR3 1Department of Pathology 2Department of Gastroscopy 3Department of Surgery Dhulikhel Hospital, Kathmandu University Hospital Dhulikhel, Kavre.
dc.description.abstractABSTRACT Background Colonoscopy is a simple, safe and well tolerated procedure, the visualization of the mucosa of the entire colon and terminal ileum to detect intestinal abnormalities and obtain biopsy leads to the early detection of the pathologic process and institution of appropriate therapy. Objective To find out the correlation between clinical and histopathological diagnosis of colorectal diseases. Method A cross-sectional study was conducted at Department of Pathology, Dhulikhel Hospital, Kathmandu University Hospital from Jan. 2015 - Jan. 2016. Altogether, 95 colonoscopic biopsies were examined and recorded clinical data using pre-designed pro forma. The specimens were grossed, processed and embedded using standard procedures, stained with Hematoxylin and Eosin stain and were analyzed using light microscope. Special stains Ziehl Neelsen, and Periodic Acid-Schiff were used whenever necessary. Result Analyses of 95 cases of colonoscopic biopsies were done. The most common clinical diagnosis was polyp in 49 cases (51.57%) and the common histopathological diagnosis was non-neoplastic polyps 31(32.63%). There was no correlation in cases for suspected infectious colitis, microscopic colitis and hemorrhoids. Conclusion Colonoscopy is incomplete without biopsy and histopathology is the gold standard for the diagnosis of colorectal lesions. The clinico-pathological correlation for neoplastic lesions was excellent. However, correlation was poor in non-neoplastic lesion. KEY WORDS Colonoscopy, colorectal lesions, histopathology
dc.identifier.urihttps://hdl.handle.net/20.500.14572/2878
dc.language.isoen_US
dc.publisherKathmandu University
dc.subjectColonoscopy
dc.subjectcolorectal lesions
dc.subjecthistopathology
dc.titleClinico-Pathological Correlation of Colorectal Diseases by Colonoscopy and Biopsy
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage178
oaire.citation.startPage173
relation.isJournalIssueOfPublication1b26738f-f35e-4559-878b-77edb14570b6
relation.isJournalIssueOfPublication.latestForDiscovery1b26738f-f35e-4559-878b-77edb14570b6
relation.isJournalOfPublicationa782b7ff-cf89-4178-ad1c-11ed89cfe1bd

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