Publication: 11β Hydroxylase Deficiency in a Child with Hypothyroidism: A Case Report
Date
2023
Article Type
Case Report
Journal Title
Journal ISSN
JNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
Volume Title
Pages
Pages: 956 - 957
Publisher
Nepal Medical Association
Abstract
Abstract
Congenital adrenal hyperplasia occurs due to enzymatic defects in the adrenocortical steroidogenesis. 11β hydroxylase deficiency is the second most common cause of congenital adrenal hyperplasia which presents with hypertension and features of androgen excess. Hypertension has also been found to cause end-organ damage in children with 11β hydroxylase deficiency. We report a case of a 10-year-old male child with hypothyroidism under thyroid replacement therapy, presenting with features of severe hypertension and androgen excess, later on, diagnosed as congenital adrenal hyperplasia due to 11β hydroxylase deficiency.
Description
Authors
Bipesh Kumar Shah
Department of Paediatrics, B.P. Koirala Institute of Health Sciences, Dharan, Sunsari, Nepal
Richa Koirala
B.P. Koirala Institute of Health Sciences, Dharan, Sunsari, Nepal
Sumit Dhamala
B.P. Koirala Institute of Health Sciences, Dharan, Sunsari, Nepal
Mukesh Bhatta
Department of Paediatrics, B.P. Koirala Institute of Health Sciences, Dharan, Sunsari, Nepal
Shekhar Khatiwada
B.P. Koirala Institute of Health Sciences, Dharan, Sunsari, Nepal
Keywords
Identifier
https://doi.org/10.31729/jnma.8378