Publication: Plexiform Schwannoma Clinically Masquerading as Thrombosed Vein
Date
2024
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Plexiform schwannoma is a rare benign nerve sheath tumor usually located in
trunk, head, neck, upper extremities and occasionally in lower extremities. It is
usually less than 2 cm in size and generally affects young adults. The tumour is
composed of schwann cells and exhibit a plexiform growth pattern both in gross
or histologic examination and is frequently accompanied by multinodularity
causing serpentine distortion. Plexiform neurofibroma commonly mimics plexiform
schwannoma and it is important to differentiate between them, as recurrence and
malignant potential are more common with plexiform neurofibroma. We present
the case of a 14-year-old female with history of a nodular soft tissue mass over his
right foot measuring 11 cm in length. A Doppler scan of the foot was suggestive
of thrombosed superficial vein in right foot. The histological evaluation of the
mass revealed Plexiform schwannoma. S-100 immunostaining is diffuse and strong
confirming the diagnosis of Plexiform schwannoma.
KEY WORDS
Hematoxylin and eosin, Histopathology, Plexiform, Schwannoma
Description
Basnet D, Makaju R, Gautam N, Shrestha B, Budhathoki A
Department of Pathology
Dhulikhel Hospital, Kathmandu University Hospital
Kathmandu University School of Medical Sciences
Dhulikhel, Kavre, Nepal
Keywords
Hematoxylin and eosin, Histopathology, Plexiform, Schwannoma