Publication: The Study of Prevalence of Helicobacter Pylori in Patients with Acne Rosacea
Date
2012
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Background
Acne rosacea is an inflammatory disease affecting the central part of the face
characterized by erythema, papules, papulo pustules and telangiectasias of
unknown etiology. More recently numerous studies have described an association
with Helicobacter pylori (Hp) and the extra gastric symptoms of cutaneous origin.
Objectives
To establish the prevalence of Helicobacter pylori (Hp) infection in the stomach in
patients with rosacea based on standard Hp serological test.
Methods
All patients with the clinical staging of 2, 3 and 4 rosacea attending the Dermatology
Out Patient Department from May 2009 – April 2010 were included in the study.
Quantitative serological test using the SERION ELISA classic Helicobacter pylori IgG
was done.
Result
A total of 26 patients were enrolled in the study with the age ranging from 26-
82 years. There were 14 males and 12 females and the male: female ratio was
1.6:1. Three (11.53%) patients presented with Grade IV rosacea, a severe clinical
presentation and symptoms suggestive of acid peptic diseases were found in 14/26
(53.8%) patients. A positive serology to H. pylori was found in 17/26 (65.4%) of
patients. A statistically significant correlation was found when association of
H.pylori positivity in patients of rosacea compared with the seropositivity in
controls. However correlation in the seropositivity was not found amongst the
patients having gastritis and rosacea.
Conclusion
There still proves to find a correlation of Hp infection with patients with rosacea
but it can still be hypothesised as a cutaneous manifestation of an internal peptic
ulcer disease .
KEY WORDS
H.pylori, rosacea
Description
Bhattarai S,1 Agrawal S,1 Rijal A,1 Majhi S,2 Pradhan B,3 Dhakal SS 3
1Department of Dermatology and Venereology
2Department of Biochemistry
3Department of Internal Medicine
B.P.Koirala Institute of Health Sciences Dharan, Nepal